ACES is a leading provider for fully Integrated chemical and biological services and products in the area of ANTIBODY DRUG CONJUGATE (ADC). We are dedicated to offer numerous payloads/linkers products and ADC conjugation services as well as in vitro and in vivo biological assay. Our proprietary acestatins and acetecans ADC platforms are composed of novel payloads (new versions of auristatins E, F and dolastatin 10, SN38, Topotecan and Exatecan derivatives) with cleavable and non-cleavable linkers. ADCs prepared from these acestatins/acetecans demonstrated the same or improved efficacy and safety profiles than ADCs from other known ADC platforms in vitro and in vivo tumor models. For the details, please click here to read more.
We provide proteins and nucleic to label antibodies, proteins, peptides, ligands and synthetic oligonucleotides and other biomolecules. These products can be directly used in the immunohistochemical, fluorescence in situ hybridization (FISH), cell tracer, receptor labeling and cell chemical application and probes of biological structure, function and interaction. These products are also powerful tools for other biotin and hapten conjugated biomolecules. Click here to view our catalog products for labeling antibody, protein, peptide and nucleic acid.
We offer numerous natural and synthetic peptides, including antigen peptides, probe peptides, inhibitory peptides. With our vast experience and state of the art facility and technology, we can efficiently make any customized peptides in a timely manner. Click here to read more.
Our antigen peptides allow the creation of peptide antibodies in animals without the need of purifying the protein of interest. Peptides have recently been used in the study of protein structure and function. Inhibitory peptides are also used in clinical research to examine the effects of peptides on the inhibition of cancer proteins and other diseases. Click here to view our catalog peptides.
We specialize in synthesizing target inhibitors, including IDO inhibitors for cancer immunotherapy, biologically-biased building blocks, especially, multi functional heterocyclic, chiral, boronic molecules. These products have been widely used in drug discovery and life science research programs from pharmaceutical, biotechnological industries and other academic research institutions. Over thirty thousands of these building blocks are available from grams to hundreds of kilograms or can be custom- synthesized efficiently. Click here to view our catalog products.